Tlc vs Column Chromatography: What Are the Differences?
Are you thinking about isolating your desired compound from a mixture? How do you know if it's time to separate your complex mixture? Even if you happen to luck into the right mixture of solvents, you could destroy your sample by trying to separate it by hand. It's better to prepare with some basic knowledge of separation techniques ahead of time. However, there seems to be a lot of confusion about the differences between TLC and column chromatography. Both of these techniques can more here https://logicalscience.com/2022/10/tlc-vs-column-chromatography-what-are-the-differences/